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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLE
All Species:
19.09
Human Site:
S2051
Identified Species:
46.67
UniProt:
Q07864
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07864
NP_006222.2
2286
261518
S2051
L
P
G
M
I
T
F
S
Q
D
Y
V
A
N
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543348
2273
260734
S2038
L
P
G
M
I
T
F
S
Q
D
Y
V
A
N
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVF7
2283
262009
S2048
L
P
G
M
I
T
F
S
Q
D
Y
V
A
N
E
Rat
Rattus norvegicus
NP_001100622
1515
174729
C1293
S
G
C
Y
S
T
V
C
V
E
L
D
I
Q
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233985
2277
260654
S2042
M
P
G
M
I
T
F
S
Q
D
Y
V
A
N
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001121995
2284
262166
S2053
L
P
G
L
I
T
F
S
Q
E
Y
V
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524462
2236
256683
E2010
N
E
C
R
E
K
F
E
S
L
L
T
L
F
M
Honey Bee
Apis mellifera
XP_393171
2183
252634
E1961
D
E
D
E
D
T
P
E
I
V
M
N
W
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002328167
2221
254636
G1993
H
M
V
E
Y
I
K
G
Q
I
G
T
H
F
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21951
2222
255653
S1995
K
K
Q
D
K
E
D
S
V
E
N
S
L
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.7
N.A.
90.5
60.7
N.A.
N.A.
83.7
N.A.
80
N.A.
55.2
54.6
N.A.
N.A.
Protein Similarity:
100
N.A.
N.A.
94.6
N.A.
95
63.5
N.A.
N.A.
92
N.A.
90.2
N.A.
71.9
71.5
N.A.
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
6.6
N.A.
N.A.
93.3
N.A.
73.3
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
13.3
N.A.
N.A.
100
N.A.
100
N.A.
6.6
13.3
N.A.
N.A.
Percent
Protein Identity:
43.5
N.A.
N.A.
N.A.
40.5
N.A.
Protein Similarity:
62.7
N.A.
N.A.
N.A.
60.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% A
% Cys:
0
0
20
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
10
10
0
10
0
0
40
0
10
0
0
0
% D
% Glu:
0
20
0
20
10
10
0
20
0
30
0
0
0
0
50
% E
% Phe:
0
0
0
0
0
0
60
0
0
0
0
0
0
20
0
% F
% Gly:
0
10
50
0
0
0
0
10
0
0
10
0
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
50
10
0
0
10
10
0
0
10
0
0
% I
% Lys:
10
10
0
0
10
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
40
0
0
10
0
0
0
0
0
10
20
0
20
0
10
% L
% Met:
10
10
0
40
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
10
0
60
10
% N
% Pro:
0
50
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
60
0
0
0
0
10
0
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
0
60
10
0
0
10
10
10
0
% S
% Thr:
0
0
0
0
0
70
0
0
0
0
0
20
0
0
10
% T
% Val:
0
0
10
0
0
0
10
0
20
10
0
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
50
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _